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The Structures of T87I Phosphono-CheY and T87I/Y106W Phosphono-CheY Help to Explain Their Binding Affinities to the FliM and CheZ Peptides
CheY is a response regulator in bacterial chemotaxis. E. coli CheY mutants T87I and T87I/Y106W CheY are phosphorylatable on Asp57 but unable to generate clockwise rotation of the flagella. To understand this phenotype in terms of structure, stable analogs of the two CheY-P mutants were synthesized:...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2850201/ https://ncbi.nlm.nih.gov/pubmed/18801331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2008.08.019 |
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