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Circadian disruption induced by light-at-night accelerates aging and promotes tumorigenesis in young but not in old rats

We evaluated the effect of exposure to constant light started at the age of 1 month and at the age of 14 months on the survival, life span, tumorigenesis and age-related dynamics of antioxidant enzymes activity in various organs in comparison to the rats maintained at the standard (12:12 light/dark)...

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Detalhes bibliográficos
Main Authors: Vinogradova, Irina A., Anisimov, Vladimir N., Bukalev, Andrey V., Ilyukha, Viktor A., Khizhkin, Evgeniy A., Lotosh, Tatiana A., Semenchenko, Anna V., Zabezhinski, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850144/
https://ncbi.nlm.nih.gov/pubmed/20354269
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