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Inhibition of Toll-Like Receptor 2-Mediated Interleukin-8 Production in Cystic Fibrosis Airway Epithelial Cells via the α7-Nicotinic Acetylcholine Receptor

Cystic Fibrosis (CF) is an inherited disorder characterised by chronic inflammation of the airways. The lung manifestations of CF include colonization with Pseudomonas aeruginosa and Staphylococcus aureus leading to neutrophil-dominated airway inflammation and tissue damage. Inflammation in the CF l...

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Main Authors: Greene, Catherine M., Ramsay, Hugh, Wells, Robert J., O'Neill, Shane J., McElvaney, Noel G.
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850130/
https://ncbi.nlm.nih.gov/pubmed/20379354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/423241
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