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Pdx1 inactivation restricted to the intestinal epithelium in mice alters duodenal gene expression in enterocytes and enteroendocrine cells

Null mutant mice lacking the transcription factor pancreatic and duodenal homeobox 1 (Pdx1) are apancreatic and survive only a few days after birth. The role of Pdx1 in regulating intestinal gene expression has therefore yet to be determined in viable mice with normal pancreatic development. We hypo...

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Detalhes bibliográficos
Main Authors: Chen, Chin, Fang, Rixun, Davis, Corrine, Maravelias, Charalambos, Sibley, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850094/
https://ncbi.nlm.nih.gov/pubmed/19808654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90586.2008
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