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Genetic and Chemical Models of Colorectal Cancer in Mice
Colorectal cancer (CRC) is a significant health concern because of its associated mortality. Most CRCs exhibit dysregulation of the Wnt signaling pathway, caused by mutational inactivation of the adenomatous polyposis coli tumor suppressor gene (APC) or mutational activation of β-catenin. Disease pr...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2850068/ https://ncbi.nlm.nih.gov/pubmed/20376303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11888-010-0046-1 |
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