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Identification of Krüppel-like factor 4 as a potential tumor suppressor gene in colorectal cancer
Krüppel-like factor 4 (KLF4 or GKLF) is an inhibitor of the cell cycle. The gene encoding KLF4 is localized on chromosome 9q, previously shown to exhibit allelic loss in colorectal cancer (CRC). In this study, we show that the mean level of KLF4 mRNA in a panel of 30 CRC was 52% that of paired norma...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1351029/ https://ncbi.nlm.nih.gov/pubmed/14724568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1207067 |
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