Bioactive products generated by group V sPLA(2) hydrolysis of LDL activate macrophages to secrete pro-inflammatory cytokines

OBJECTIVE: Previous studies have established that hydrolysis of LDL by Group V secretory phospholipase A(2) (GV sPLA(2)) generates a modified particle capable of inducing macrophage foam cell formation. The aim of the present study was to determine whether GV sPLA(2)-hydrolyzed LDL (GV-LDL) produces...

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Hlavní autoři: Boyanovsky, Boris B., Li, Xia, Shridas, Preetha, Sunkara, Manjula, Morris, Andrew J., Webb, Nancy R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850046/
https://ncbi.nlm.nih.gov/pubmed/20138782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2009.12.009
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