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Antigen-specific Treg regulate Th17-mediated lung neutrophilic inflammation, B cell recruitment and polymeric IgA and IgM levels in the airways

Th17 cells play key roles in mediating autoimmunity, inflammation and mucosal host defense against pathogens. To determine whether naturally occurring Treg (nTreg) limit Th17-mediated pulmonary inflammation, OVA-specific CD4(+) Th17 cells and expanded CD4(+)CD25(+)Foxp3(+) nTreg were cotransferred i...

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Hlavní autoři: Jaffar, Zeina, Ferrini, Maria E., Girtsman, Teri A., Roberts, Kevan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849980/
https://ncbi.nlm.nih.gov/pubmed/19830731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200939498
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