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Lab-on-a-chip for botulinum neurotoxin a (BoNT-A) activity analysis

A Lab-on-a-chip (LOC) was designed, fabricated and tested for the in vitro detection of botulinum neurotoxin serotype A (BoNT-A) activity using an assay that measures cleavage of a fluorophore-tagged peptide substrate specific for BoNT-A (SNAP-25) by the toxin light chain (LcA). LcA cleavage was det...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sun, Steven, Ossandon, Miguel, Kostov, Yordan, Rasooly, Avraham
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849933/
https://ncbi.nlm.nih.gov/pubmed/19865736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b912097a
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