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Orexin signaling via the orexin 1 receptor mediates operant responding for food reinforcement

BACKGROUND: Orexin (hypocretin) signaling is implicated in drug addiction and reward, but its role in feeding and food-motivated behavior remains unclear. METHODS: We investigated orexin’s contribution to food-reinforced instrumental responding using an orexin 1 receptor (Ox1r) antagonist, orexin −/...

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Detalles Bibliográficos
Main Authors: Sharf, Ruth, Sarhan, Maysa, Brayton, Catherine E., Guarnieri, Douglas J., Taylor, Jane R., DiLeone, Ralph J.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849869/
https://ncbi.nlm.nih.gov/pubmed/20189166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2009.12.035
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