IgG antibodies produced during subcutaneous allergen immunotherapy mediate inhibition of basophil activation via a mechanism involving both FcγRIIA and FcγRIIB

The majority of human subjects who receive subcutaneous allergen immunotherapy (IT) develop decreased sensitivity to their allergens. Multiple factors may explain the efficacy of IT, some evidence supports a role for allergen specific IgG antibodies. There is controversy whether such antibodies act...

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Autors principals: Cady, Carol T., Powell, Maree S., Harbeck, Ronald J, Giclas, Patricia C, Murphy, James R, Katial, Rohit K, Weber, Richard W, Hogarth, P. Mark, Johnson, Syd, Bonvini, Ezio, Koenig, Scott, Cambier, John C
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849848/
https://ncbi.nlm.nih.gov/pubmed/20004689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2009.12.001
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