IgG antibodies produced during subcutaneous allergen immunotherapy mediate inhibition of basophil activation via a mechanism involving both FcγRIIA and FcγRIIB

The majority of human subjects who receive subcutaneous allergen immunotherapy (IT) develop decreased sensitivity to their allergens. Multiple factors may explain the efficacy of IT, some evidence supports a role for allergen specific IgG antibodies. There is controversy whether such antibodies act...

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Main Authors: Cady, Carol T., Powell, Maree S., Harbeck, Ronald J, Giclas, Patricia C, Murphy, James R, Katial, Rohit K, Weber, Richard W, Hogarth, P. Mark, Johnson, Syd, Bonvini, Ezio, Koenig, Scott, Cambier, John C
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849848/
https://ncbi.nlm.nih.gov/pubmed/20004689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2009.12.001
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