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Effect of HEPES buffer on the uptake and transport of P-glycoprotein substrates and large neutral amino acids

HEPES has been widely employed as an organic buffer agent in cell culture medium as well as uptake and transport experiments in vitro. However, concentrations of HEPES used in such studies vary from one laboratory to another. In this study, we investigated the effect of HEPES on the uptake and bidir...

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Autori principali: Luo, Shuanghui, Pal, Dhananjay, Shah, Sujay J., Kwatra, Deep, Paturi, Kalyani D., Mitra, Ashim. K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849840/
https://ncbi.nlm.nih.gov/pubmed/20163160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp900193e
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