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Downregulation of Kv4.2 channels mediated by NR2B-containing NMDA receptors in cultured hippocampal neurons
Somatodendritic Kv4.2 channels mediate transient A-type potassium currents (I(A)), and play critical roles in controlling neuronal excitability and modulating synaptic plasticity. Our studies have shown a NMDA receptor-dependent downregulation of Kv4.2 and I(A). NMDA receptors are heteromeric comple...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2849736/ https://ncbi.nlm.nih.gov/pubmed/19857555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2009.10.041 |
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