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Guanidine Hydrochloride-Induced Unfolding of the Three Heme Coordination States of the CO-Sensing Transcription Factor, CooA

CooA is a heme-dependent CO-sensing transcription factor that has three observable heme coordination states. There is some evidence that each CooA heme state has a distinct protein conformation; the goal of this study was to characterize these conformations by measurement of their structural stabili...

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Detalhes bibliográficos
Main Authors: Lee, Andrea J., Clark, Robert W., Youn, Hwan, Ponter, Sarah, Burstyn, Burstyn
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849680/
https://ncbi.nlm.nih.gov/pubmed/19594171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801827j
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