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Trafficking of TrkA-Green Fluorescent Protein Chimerae during Nerve Growth Factor-induced Differentiation

A chimera of the nerve growth factor (NGF) receptor, TrkA, and green fluorescent protein (GFP) was engineered by expressing GFP in phase with the carboxyl terminus of TrkA. TrkA-GFP becomes phosphorylated on tyrosine residues in response to NGF and is capable of initiating signaling cascades leading...

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Detalhes bibliográficos
Main Authors: Jullien, Jérôme, Guili, Vincent, Derrington, Edmund A., Darlix, Jean-Luc, Reichardt, Louis F., Rudkin, Brian B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849666/
https://ncbi.nlm.nih.gov/pubmed/12438306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M202401200
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