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Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

In contrast to normal differentiated cells, which rely primarily on mitochondrial oxidative phosphorylation to generate the energy needed for cellular processes, most cancer cells instead rely on aerobic glycolysis, a phenomenon termed “the Warburg effect.” Aerobic glycolysis is an inefficient way t...

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Detalhes bibliográficos
Main Authors: Vander Heiden, Matthew G., Cantley, Lewis C., Thompson, Craig B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849637/
https://ncbi.nlm.nih.gov/pubmed/19460998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1160809
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