Hepatitis E Virus (HEV) Strains in Serum Samples Can Replicate Efficiently in Cultured Cells Despite the Coexistence of HEV Antibodies: Characterization of HEV Virions in Blood Circulation

We recently developed a cell culture system for hepatitis E virus (HEV) in PLC/PRF/5 and A549 cells, using fecal specimens from HEV-infected patients. Since transfusion-associated hepatitis E has been reported, we examined PLC/PRF/5 and A549 cells for the ability to support replication of HEV in var...

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Main Authors: Takahashi, Masaharu, Tanaka, Toshinori, Takahashi, Hideyuki, Hoshino, Yu, Nagashima, Shigeo, Jirintai, Mizuo, Hitoshi, Yazaki, Yasuyuki, Takagi, Tomofumi, Azuma, Masahiro, Kusano, Eiji, Isoda, Norio, Sugano, Kentaro, Okamoto, Hiroaki
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Virology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849599/
https://ncbi.nlm.nih.gov/pubmed/20107086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.02002-09
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