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Strains of the East Asian (W/Beijing) Lineage of Mycobacterium tuberculosis Are DosS/DosT-DosR Two-Component Regulatory System Natural Mutants

As part of our ongoing efforts to uncover the phenotypic consequences of genetic variability among clinical Mycobacterium tuberculosis isolates, we previously reported that isolates of the “East Asian” or “W/Beijing” lineage constitutively overexpress the coordinately regulated transcriptional progr...

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Autori principali: Fallow, Ashley, Domenech, Pilar, Reed, Michael B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849454/
https://ncbi.nlm.nih.gov/pubmed/20154135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01597-09
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