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GroEL and Lipopolysaccharide from Francisella tularensis Live Vaccine Strain Synergistically Activate Human Macrophages

Francisella tularensis, the causative agent of tularemia, interacts with host cells of innate immunity in an atypical manner. For most Gram-negative bacteria, the release of lipopolysaccharide (LPS) from their outer membranes stimulates an inflammatory response. When LPS from the attenuated live vac...

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Bibliografiske detaljer
Main Authors: Noah, Courtney E., Malik, Meenakshi, Bublitz, DeAnna C., Camenares, Devin, Sellati, Timothy J., Benach, Jorge L., Furie, Martha B.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849404/
https://ncbi.nlm.nih.gov/pubmed/20123721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01135-09
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