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GroEL and Lipopolysaccharide from Francisella tularensis Live Vaccine Strain Synergistically Activate Human Macrophages

Francisella tularensis, the causative agent of tularemia, interacts with host cells of innate immunity in an atypical manner. For most Gram-negative bacteria, the release of lipopolysaccharide (LPS) from their outer membranes stimulates an inflammatory response. When LPS from the attenuated live vac...

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Main Authors: Noah, Courtney E., Malik, Meenakshi, Bublitz, DeAnna C., Camenares, Devin, Sellati, Timothy J., Benach, Jorge L., Furie, Martha B.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849404/
https://ncbi.nlm.nih.gov/pubmed/20123721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01135-09
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