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Fasting Increases Tobramycin Oral Absorption in Mice
The pharmacokinetics of the aminoglycoside tobramycin was evaluated after oral administration to fed or fasting (15 h) mice. As expected, under normal feeding conditions, oral absorption was negligible; however, fasting induced a dramatic increase in tobramycin bioavailability. The dual-sugar test w...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology (ASM)
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2849372/ https://ncbi.nlm.nih.gov/pubmed/20086144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01172-09 |
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