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IL-12 induces salivary gland dysfunction, providing a new mouse model of Sjögren's syndrome
OBJECTIVE: Interleukin-12 (IL-12) is a pleiotropic cytokine and is elevated in affected organs of Sjögren's syndrome (SS) patients. We have previously reported in CBA mice that over-expression of IL-12 leads to mononuclear infiltration of salivary and lacrimal glands, as well as expansion of br...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2849131/ https://ncbi.nlm.nih.gov/pubmed/19950301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.24980 |
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