ロード中...
Mutation of Glu-166 Blocks the Substrate-Induced Dimerization of SARS Coronavirus Main Protease
The maturation of SARS coronavirus involves the autocleavage of polyproteins 1a and 1ab by the main protease (Mpro) and a papain-like protease; these represent attractive targets for the development of anti-SARS drugs. The functional unit of Mpro is a homodimer, and each subunit has a His-41⋯Cys-145...
保存先:
| 主要な著者: | , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Biophysical Society
2010
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2849084/ https://ncbi.nlm.nih.gov/pubmed/20371333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.12.4272 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|