טוען...
Design and characterization of a constitutively open KcsA
The molecular nature of the structure responsible for proton sensitivity in KcsA has been identified as a charge cluster that surrounds the inner helical bundle gate. Here, we show that this proton sensor can be modified to engineer a constitutively open form of KcsA, amenable to functional, spectro...
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| Main Authors: | , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2010
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2848999/ https://ncbi.nlm.nih.gov/pubmed/20153331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2010.02.015 |
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