A siRNA Screen of Genes Involved in DNA Repair Identifies Tumour Specific Radiosensitisation by POLQ Knockdown

The effectiveness of radiotherapy treatment could be significantly improved if tumour cells could be rendered more sensitive to ionizing radiation without altering the sensitivity of normal tissues. However many of the key, therapeutically exploitable mechanisms that determine intrinsic tumour radio...

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Bibliographische Detailangaben
Hauptverfasser: Higgins, Geoff S, Prevo, Remko, Lee, Yin-Fai, Helleday, Thomas, Muschel, Ruth J, Taylor, Steve, Yoshimura, Michio, Hickson, Ian D, Bernhard, Eric J, McKenna, W Gillies
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848966/
https://ncbi.nlm.nih.gov/pubmed/20233878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-4040
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