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Functional Axonal Regeneration through Astrocytic Scar Genetically Modified to Digest Chondroitin Sulfate Proteoglycans

Axotomized neurons within the damaged CNS are thought to be prevented from functional regeneration by inhibitory molecules such as chondroitin sulfate proteoglycans (CSPGs) and myelin-associated inhibitors. Here, we provide a transgenic test of the role of CSPGs in limiting regeneration, using the g...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cafferty, William B. J., Yang, Shih-Hung, Duffy, Philip J., Li, Shuxin, Strittmatter, Stephen M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848955/
https://ncbi.nlm.nih.gov/pubmed/17329414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5176-06.2007
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