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Functional Axonal Regeneration through Astrocytic Scar Genetically Modified to Digest Chondroitin Sulfate Proteoglycans

Axotomized neurons within the damaged CNS are thought to be prevented from functional regeneration by inhibitory molecules such as chondroitin sulfate proteoglycans (CSPGs) and myelin-associated inhibitors. Here, we provide a transgenic test of the role of CSPGs in limiting regeneration, using the g...

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Detalhes bibliográficos
Main Authors: Cafferty, William B. J., Yang, Shih-Hung, Duffy, Philip J., Li, Shuxin, Strittmatter, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848955/
https://ncbi.nlm.nih.gov/pubmed/17329414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5176-06.2007
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