ANTITUMOR ACTIVITY OF HYALURONIC ACID SYNTHESIS INHIBITOR 4-METHYLUMBELLIFERONE IN PROSTATE CANCER CELLS

4-methylumbelliferone (4-MU) is a hyaluronic acid (HA) synthesis inhibitor with anticancer properties; the mechanism of its anticancer effects is unknown. We evaluated the effects of 4-MU on prostate cancer cells. 4-MU inhibited proliferation, motility and invasion of DU145, PC3-ML, LNCaP, C4-2B and...

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Bibliografiske detaljer
Main Authors: Lokeshwar, Vinata B., Lopez, Luis E., Munoz, Daniel, Chi, Andrew, Shirodkar, Samir P., Lokeshwar, Soum D., Escudero, Diogo O., Dhir, Neetika, Altman, Norman
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848908/
https://ncbi.nlm.nih.gov/pubmed/20332231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3185
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