Antitumor activity of sulfated hyaluronic acid fragments in pre-clinical models of bladder cancer

Tumor cell-derived hyaluronidase HYAL-1 degrades hyaluronic acid (HA) into angiogenic fragments (AGF: 10-12 disaccharides). AGF support tumor growth and progression. Urine and tissue HAase/HYAL-1 levels are sensitive markers for high-grade bladder cancer (BCa) and its metastasis. In preclinical mode...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncotarget
Egile Nagusiak: Jordan, Andre R., Lokeshwar, Soum D., Lopez, Luis E., Hennig, Martin, Chipollini, Juan, Yates, Travis, Hupe, Marie C., Merseburger, Axel S., Shiedlin, Aviva, Cerwinka, Wolfgang H., Liu, Kebin, Lokeshwar, Vinata B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2016
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5421845/
https://ncbi.nlm.nih.gov/pubmed/27419371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10529
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