Simultaneous Induction of Non-Canonical Autophagy and Apoptosis in Cancer Cells by ROS-Dependent ERK and JNK Activation

BACKGROUND: Chemotherapy-induced reduction in tumor load is a function of apoptotic cell death, orchestrated by intracellular caspases. However, the effectiveness of these therapies is compromised by mutations affecting specific genes, controlling and/or regulating apoptotic signaling. Therefore, it...

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Detaylı Bibliyografya
Asıl Yazarlar: Wong, Chew Hooi, Iskandar, Kartini Bte, Yadav, Sanjiv Kumar, Hirpara, Jayshree L., Loh, Thomas, Pervaiz, Shazib
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2010
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848860/
https://ncbi.nlm.nih.gov/pubmed/20368806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009996
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