Deep Sequencing of Target Linkage Assay-Identified Regions in Familial Breast Cancer: Methods, Analysis Pipeline and Troubleshooting

BACKGROUND: The classical candidate-gene approach has failed to identify novel breast cancer susceptibility genes. Nowadays, massive parallel sequencing technology allows the development of studies unaffordable a few years ago. However, analysis protocols are not yet sufficiently developed to extrac...

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Main Authors: Rosa-Rosa, Juan Manuel, Gracia-Aznárez, Francisco Javier, Hodges, Emily, Pita, Guillermo, Rooks, Michelle, Xuan, Zhenyu, Bhattacharjee, Arindam, Brizuela, Leonardo, Silva, José M., Hannon, Gregory J., Benitez, Javier
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848842/
https://ncbi.nlm.nih.gov/pubmed/20368986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009976
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