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Tryptophan Scanning Analysis of the Membrane Domain of CTR-Copper Transporters

Membrane proteins of the CTR family mediate cellular copper uptake in all eukaryotic cells and have been shown to participate in uptake of platinum-based anticancer drugs. Despite their importance for life and the clinical treatment of malignancies, directed biochemical studies of CTR proteins have...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: De Feo, Christopher J., Mootien, Sara, Unger, Vinzenz M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer-Verlag 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848729/
https://ncbi.nlm.nih.gov/pubmed/20224886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00232-010-9239-4
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