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p53 Suppresses Structural Chromosome Instability Following Mitotic Arrest In Human Cells

The p53 tumor suppressor inhibits the proliferation of cells which undergo prolonged activation of the mitotic checkpoint. However, the function of this antiproliferative response is not well defined. Here we report that p53 suppresses structural chromosome instability following mitotic arrest in hu...

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Detalhes bibliográficos
Main Authors: Dalton, W. Brian, Yu, Bing, Yang, Vincent W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848712/
https://ncbi.nlm.nih.gov/pubmed/20062083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.477
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