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Involvement of p53 in cell death following cell cycle arrest and mitotic catastrophe induced by rotenone
In order to investigate the cell death-inducing effects of rotenone, a plant extract commonly used as a mitochondrial complex I inhibitor, we studied cancer cell lines with different genetic backgrounds. Rotenone inhibits cell growth through the induction of cell death and cell cycle arrest, associa...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3051352/ https://ncbi.nlm.nih.gov/pubmed/21223980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2011.01.006 |
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