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Involvement of p53 in cell death following cell cycle arrest and mitotic catastrophe induced by rotenone

In order to investigate the cell death-inducing effects of rotenone, a plant extract commonly used as a mitochondrial complex I inhibitor, we studied cancer cell lines with different genetic backgrounds. Rotenone inhibits cell growth through the induction of cell death and cell cycle arrest, associa...

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Detalhes bibliográficos
Main Authors: Gonçalves, António Pedro, Máximo, Valdemar, Lima, Jorge, Singh, Keshav K., Soares, Paula, Videira, Arnaldo
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3051352/
https://ncbi.nlm.nih.gov/pubmed/21223980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2011.01.006
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