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Enrichment and Characterization of Histones by 2D-Hydroxyapatite/Reversed-Phase Liquid Chromatography Mass Spectrometry
Here we report a novel two-dimensional LC-MS method that combines offline hydroxyapatite (HA) chromatography with online reversed-phase liquid chromatography mass spectrometry (HA/RP LC-MS). The 2D-LC-MS method was used to enrich and characterize histones and their posttranslational modifications. T...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2848711/ https://ncbi.nlm.nih.gov/pubmed/19454230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2009.01.033 |
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