Highly Frequent Mutations in Negative Regulators of Multiple Virulence Genes in Group A Streptococcal Toxic Shock Syndrome Isolates

Streptococcal toxic shock syndrome (STSS) is a severe invasive infection characterized by the sudden onset of shock and multiorgan failure; it has a high mortality rate. Although a number of studies have attempted to determine the crucial factors behind the onset of STSS, the responsible genes in gr...

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Bibliografiske detaljer
Main Authors: Ikebe, Tadayoshi, Ato, Manabu, Matsumura, Takayuki, Hasegawa, Hideki, Sata, Tetsutaro, Kobayashi, Kazuo, Watanabe, Haruo
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848555/
https://ncbi.nlm.nih.gov/pubmed/20368967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000832
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