Protease-Activated Receptor-1 Contributes to Cardiac Remodeling and Hypertrophy

BACKGROUND: Protease-activated receptor-1 (PAR-1) is the high-affinity receptor for the coagulation protease thrombin. It is expressed by a variety of cell types in the heart, including cardiomyocytes and cardiac fibroblasts. We have shown that tissue factor (TF) and thrombin contribute to infarct s...

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Main Authors: Pawlinski, Rafal, Tencati, Michael, Hampton, Craig R., Shishido, Tetsuro, Bullard, Tara A., Casey, Liam M., Andrade-Gordon, Patricia, Kotzsch, Matthias, Spring, Denise, Luther, Thomas, Abe, Jun-ichi, Pohlman, Timothy H., Verrier, Edward D., Blaxall, Burns C., Mackman, Nigel
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848478/
https://ncbi.nlm.nih.gov/pubmed/17967980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.107.692764
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