Pharmacokinetic and pharmacodynamic analysis of enteric-coated mycophenolate sodium: limited sampling strategies and clinical outcome in renal transplant patients

AIMS: Pharmacokinetic (PK) and pharmacodynamic (PD) monitoring strategies and clinical outcome were evaluated in enteric-coated mycophenolate sodium (EC-MPS)-treated renal allograft recipients. METHODS: PK [mycophenolic acid (MPA)] and PD [inosine monophosphate dehydrogenase (IMPDH) activity] data w...

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Detalhes bibliográficos
Main Authors: Sommerer, Claudia, Müller-Krebs, Sandra, Schaier, Matthias, Glander, Petra, Budde, Klemens, Schwenger, Vedat, Mikus, Gerd, Zeier, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Pharmacokinetic Dynamic Relationships
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848408/
https://ncbi.nlm.nih.gov/pubmed/20406219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2009.03612.x
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