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Semi-quantitative Assessment of Microdistribution of Fluorescence-labeled Monoclonal Antibody in Small Peritoneal Disseminations of Ovarian Cancer

Uniform antibody microdistribution throughout tumor nodules is crucial for antibody-targeted therapy, because nonuniform microdistribution leads to suboptimal therapeutic effect, a commonly observed limitation of therapeutic antibodies. Herein, we evaluated the microdistribution of different doses o...

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Bibliographic Details
Main Authors: Kosaka, Nobuyuki, Ogawa, Mikako, Paik, David S., Paik, Chang H., Choyke, Peter L., Kobayashi, Hisataka
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848296/
https://ncbi.nlm.nih.gov/pubmed/19961490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2009.01423.x
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