Epithelial Protein Lost in Neoplasm α (Eplin-α) is transcriptionally regulated by G-actin and MAL/MRTF coactivators

Epithelial Protein Lost in Neoplasm α is a novel cytoskeleton-associated tumor suppressor whose expression inversely correlates with cell growth, motility, invasion and cancer mortality. Here we show that Eplin-α transcription is regulated by actin-MAL-SRF signalling. Upon signal induction, the coac...

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Bibliografiske detaljer
Main Authors: Leitner, Laura, Shaposhnikov, Dmitry, Descot, Arnaud, Hoffmann, Reinhard, Posern, Guido
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Short communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848193/
https://ncbi.nlm.nih.gov/pubmed/20236507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-60
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