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GCN5-dependent acetylation of HIV-1 integrase enhances viral integration
BACKGROUND: An essential event during the replication cycle of HIV-1 is the integration of the reverse transcribed viral DNA into the host cellular genome. Our former report revealed that HIV-1 integrase (IN), the enzyme that catalyzes the integration reaction, is positively regulated by acetylation...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
BioMed Central
2010
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2848186/ https://ncbi.nlm.nih.gov/pubmed/20226045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-7-18 |
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