Discovery and SAR exploration of N-aryl-N-(3-aryl-1,2,4-oxadiazol-5-yl)amines as potential therapeutic agents for prostate cancer

A new chemical series of antiproliferative compounds was identified via high-throughput screening on DU-145 human prostate carcinoma cell line (hit compound potency - 5.7 μM). Exploration of the two peripheral diversity vectors of the hit molecule in a hit-targeted library and testing of the resulti...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Krasavin, Mikhail, Rufanov, Konstantin A, Sosnov, Andrey V, Karapetian, Ruben, Godovykh, Elena, Soldatkina, Olga, Lavrovsky, Yan, Gakh, Andrei A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Preliminary Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848039/
https://ncbi.nlm.nih.gov/pubmed/20214785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-153X-4-4
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados