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The Erk2 MAPK Regulates CD8 T Cell Proliferation and Survival

The magnitude of T cell responses is determined by proliferation and survival decisions made by the responding cells. We now demonstrate that the Erk MAPK pathway plays a critical role in these cell fate decisions within CD8 T cells. While Erk1 is dispensable for all aspects of CD8 T cell activation...

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Autors principals: D'Souza, Warren N., Chang, Chiung-Fang, Fischer, April M., Li, Manqing, Hedrick, Stephen M.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847891/
https://ncbi.nlm.nih.gov/pubmed/19017950
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