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Gangliosides That Associate with Lipid Rafts Mediate Transport of Cholera and Related Toxins from the Plasma Membrane to Endoplasmic Reticulm

Cholera toxin (CT) travels from the plasma membrane of intestinal cells to the endoplasmic reticulum (ER) where a portion of the A-subunit, the A1 chain, crosses the membrane into the cytosol to cause disease. A related toxin, LTIIb, binds to intestinal cells but does not cause toxicity. Here, we sh...

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Udgivet i:Mol Biol Cell
Principais autores: Fujinaga, Yukako, Wolf, Anne A., Rodighiero, Chiara, Wheeler, Heidi, Tsai, Billy, Allen, Larry, Jobling, Michael G., Rapoport, Tom, Holmes, Randall K., Lencer, Wayne I.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Cell Biology 2003
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Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284783/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/13679513/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E03-06-0354
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