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A complex 3D human tissue culture system based on mammary stromal cells and silk scaffolds for modeling breast morphogenesis and function

Epithelial-stromal interactions play a crucial role in normal embryonic development and carcinogenesis of the human breast while the underlying mechanisms of these events remain poorly understood. To address this issue, we constructed a physiologically relevant, three-dimensional (3D) culture surrog...

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Detalhes bibliográficos
Main Authors: Wang, Xiuli, Sun, Lin, Maffini, Maricel V., Soto, Ana, Sonnenschein, Carlos, Kaplan, David L
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847607/
https://ncbi.nlm.nih.gov/pubmed/20185172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2010.01.118
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