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The microenvironment determines the breast cancer cells' phenotype: organization of MCF7 cells in 3D cultures

BACKGROUND: Stromal-epithelial interactions mediate breast development, and the initiation and progression of breast cancer. In the present study, we developed 3-dimensional (3D) in vitro models to study breast cancer tissue organization and the role of the microenvironment in phenotypic determinati...

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Detalhes bibliográficos
Main Authors: Krause, Silva, Maffini, Maricel V, Soto, Ana M, Sonnenschein, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897802/
https://ncbi.nlm.nih.gov/pubmed/20529269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-263
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