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Intracellular penetration and activity of BAY Y 3118 in human polymorphonuclear leukocytes.

The penetration of a new quinolone (BAY Y 3118) into human polymorphonuclear leukocytes (PMNs) was evaluated by a fluorometric assay. The cellular concentration-to-extracellular concentration (C/E) ratio was higher than 6.3 at extracellular concentrations ranging from 2 to 100 mg/liter. The uptake o...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: García, I, Pascual, A, Perea, E J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284756/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7840582/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.10.2426
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