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Diabetes-Induced Oxidative Stress Is Mediated by Ca(2+)-Independent Phospholipase A2 in Neutrophils
Neutrophils from people with poorly controlled diabetes present a primed phenotype and secrete excessive superoxide. Phospholipase A(2) (PLA(2))-derived arachidonic acid (AA) activates the assembly of NADPH oxidase to generate superoxide anion. There is a gap in the current literature regarding whic...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2847507/ https://ncbi.nlm.nih.gov/pubmed/20053941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901219 |
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