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The origins and impact of primate segmental duplications

Duplicated sequences are substrates for the emergence of new genes and are an important source of genetic instability associated with rare and common diseases. Analyses of primate genomes have shown an increase in the proportion of interspersed segmental duplications (SDs) within the genomes of huma...

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Autors principals: Marques-Bonet, Tomas, Girirajan, Santhosh, Eichler, Evan E.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847396/
https://ncbi.nlm.nih.gov/pubmed/19796838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2009.08.002
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